Search results for " downstream processing"
Article
QbD and PAT in Upstream and Downstream Processing
The big difference is that the ease of measurement of these attributes improves significantly in downstream processing as the samples are relatively cleaner.
BioPharm: In implementing QbD, what…
Article
Addressing the Complex Nature of Downstream Processing with QbD
Challenges of QbD in downstream processing
With the complex nature of biologics comes more complex quality concerns. Joey Studts, director late-stage downstream development in the bioprocessing d…
Article
Addressing the Challenges in Downstream Processing Today and Tomorrow
The increasing volumes, cell densities, and protein masses have posed numerous new challenges for downstream processing.
ADDRESSING CHALLENGES IN mAb PROCESSING
Shrinking timelines have neces…
Article
Process Chromatography Selection for Downstream Processing Applications
Selecting the appropriate separation technology plays a big role in maximizing productivity in any downstream processing application. Some factors companies may consider when selecting a separation te…
Article
Downstream Processing Continues to Worry CMOs
In fact, nearly two-thirds (64%) of CMOs surveyed for the study report at least some bottleneck problems due to downstream processing.
Impact of downstream processing
Downstream processing p…
Article
Trends in Downstream Bioprocessing
…nology Industry Council confirmed that a leading 24% of bioprocessing decision-makers indicated that downstream processing would be the biggest trend in 2013 (1).
Although much of the discussion …
Article
Downstream Processing for Cell-Based Therapies
…ge-scale cell expansion; however, equally important is the development of large-scale harvesting and downstream processing operations. This paper presents and summarizes some of the challenges associ…
Article
Using Single-Use Technologies in Downstream Processing
Mehta states that the use of SUS in downstream processing may “reduce risk of cross contamination and carryover due to inadequate cleaning steps.”
BioPharm International spoke with Nilesh Mehta ab…
Article
Single-Use for Downstream Chromatography: Benefit or Hindrance?
Single-use technology is gaining ground in downstream bioprocessing, but challenges stall further adoption.
By Feliza Mirasol
ARTMOIS/STOCK.ADOBE.COM
Biopharmaceutical manufactu…
Article
SEC in the Modern Downstream Purification Process
Mar 01, 2015
By R. Christopher Manzari, J. Kevin O'Donnell
BioPharm International
Volume 3, Issue 28
Since the introduction of commercial chromatography resins approximately six de…